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Spermidine is a natural low molecular weight polyamine widely distributed in various organisms.

It has a high capacity to promote the reparative effect of periodontal, bone and dental tissue damaged by the erosive effects of periodontitis.
The structural feature is crucial for its functions, which include DNA stabilization, promotion of cell growth, and induction of autophagya.

Ubigel activates the mechanistic action of the connective tissue cells by stimulating the exchange and production of proteins that promote cellular activities for the well-being of the periodontist without altering its morphology and inducing the healing of the gums from the periodontitis.

In vitro characterization of the effect of UBIGEL on human gingival fibroblasts.

Prof. Nicoletta Gagliano
Department of Biomedical Sciences for Health University of Milan, 15 July 2021